Myelopathy due to Spinal Extramedullary Hematopoiesis in a Patient with Polycythemia Vera

Subacute compressive myelopathy secondary to extramedullary hematopoiesis.

A 25-year-old man presented with subacute onset paraparesis with sphincter disturbance. His past medical history unvealed b-thalassemia intermedia (compound heterozygote IVS 1-5) and hereditary persistence of fetal hemoglobin type 2. His neurological examination disclosed a complete spinal cord syndrome without clear thoracic sensory level. Spinal cord imaging showed severe thoracic spinal sten...

Cord compression by extramedullary hematopoiesis in polycythemia vera.

Paraspinal and Presacral Extramedullary Hematopoiesis: A Rare Manifestation of Polycythemia Vera

Extramedullary hematopoiesis is characterized by the presence of hematopoietic tissue outside the bone marrow. Extrathoracic extramedullary hematopoiesis is a rare and usually asymptomatic condition. We report a case of a 38-year-old female with paraspinal and presacral extramedullary hematopoiesis with polycythemia vera. Clinical and laboratory evaluation, along with radiological and histopath...

Paraplegia due to Extramedullary Hematopoietic Tissue Compression of Thoracic Thecal Sac in a Patient with Thalassemia Treated Successfully with Surgical Decompression: A Case Report

Spinal cord compression due to extramedullary hematopoiesis (EMH) is a rare complication of thalassemia and generally presents as paraparesis with sensory impairment.1 Complete paraplegia is extremely rare in EMH due to thalassemia although it is known to occur in polycythemia vera and sickle cell anemia.2 Cases presenting with paraparesis have been treated with either surgery or radiotherapy3 ...

Paravertebral Extramedullary Hematopoiesis In A Pregnant Thalassemic Patient: A Case Report

Spinal cord compression due to extramedullary hematopoiesis is a well-described and rare syndrome encountered in several hematological disorders including β-thalassemia. Hereby, a 37-year old pregnant woman with intermediate β -thalassemia with paraparesis and lower limb hypoesthesia was presented. MRI s...